Neuropeptide Y Receptors. Future Therapeutic Target in Congestive Heart Failure.
نویسندگان
چکیده
منابع مشابه
Renal and cardiac neuropeptide Y and NPY receptors in a rat model of congestive heart failure.
Neuropeptide Y (NPY) is coreleased with norepinephrine and stimulates vasoconstriction, vascular and cardiomyocyte hypertrophy via Y1 receptors (R) and angiogenesis via Y2R. Although circulating NPY is elevated in heart failure, NPY's role remains unclear. Activation of the NPY system was determined in Wistar rats with the aortocaval (A-V) fistula model of high-output heart failure. Plasma NPY ...
متن کاملRenal and Cardiac Neuropeptide Y (NPY) and NPY Receptors in a Rat Model of Congestive Heart Failure
Neuropeptide Y (NPY) is co-released with norepinephrine, and stimulates vasoconstriction, vascular and cardiomyocyte hypertrophy via Y1 receptors (R), and angiogenesis via Y2R. Although circulating NPY is elevated in heart failure, NPY’s role remains unclear. Activation of the NPY system was determined in Wistar rats with the aortocaval (AV) fistula model of high-output heart failure. Plasma NP...
متن کاملCardiac neuropeptide Y and noradrenaline balance in patients with congestive heart failure.
OBJECTIVE To measure plasma concentrations of noradrenaline and neuropeptide Y-like immunoreactivity in relation to cardiac function in patients with congestive heart failure. DESIGN Retrospective analysis of plasma noradrenaline concentrations and neuropeptide Y-like immunoreactivity in the arterial and coronary circulations, in patients with a high or low ejection fraction (31.3% (1.3%) or ...
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During a period of four years between June, IS, 1988 to June, IS, 1992 one hundred and fourteen patients with congestive heart failure (CHF) were admitted to the pediatric department of Taleghani General Hospital. During the above period, 192 patients with heart disease were hospitalized at this department and CHF was the cause of admission in 59.4% of them. Congenital heart disease (CHO) w...
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Congestive heart failure (CHF) is characterized by impaired left ventricular function, increased peripheral and pulmonary vascular resistance and reduced exercise tolerance and dyspnea. Thus, mediators involved in the control of myocardial function and vascular tone may be involved in its pathophysiology. The family of endothelins (ET) consists of four closely related peptides, ET-1, ET-2, ET-3...
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ژورنال
عنوان ژورنال: Journal of Health Science
سال: 2000
ISSN: 1344-9702,1347-5207
DOI: 10.1248/jhs.46.430